| 41549 | Q4LBB9 | OCTB2_DROME | Octopamine receptor beta-2R (DmOct-beta-12) (DmOct-beta-2R) | DISRUPTION PHENOTYPE | Males appear viable and fertile whereas females are sterile (PubMed:25099506, PubMed:25353988). Female pre- and post-mating behaviors, such as courtship and post-mating rejection, are not affected and sperm storage appears normal (PubMed:25099506, PubMed:25353988). However, ovulation and egg-laying is severely impaired and females display a strong delay in copulation rates (PubMed:25099506, PubMed:25353988). Ovaries are enlarged due to a higher number of retained eggs and the small number of eggs that are laid are not fertilized (PubMed:25353988). Larvae fail to respond to starvation by increasing locomotor activity (PubMed:21186359). Reduced growth of octopaminergic and glutamatergic (type I and type II) neuromuscular junctions (PubMed:21186359). Decrease in the number of terminal type I and type II boutons and in the motile filopodia-like extensions (synaptopods) which form during the expansion of type II terminals in developing larvae (PubMed:21186359). {ECO:0000269|PubMed:21186359, ECO:0000269|PubMed:25099506, ECO:0000269|PubMed:25353988}. |