Mine Disruption Phenotype

Gene Info

  • Species:Fly (Drosophila melanogaster)
  • GeneID:42737
  • Symbol:hh
  • Description:hedgehog
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Gene ID Entry Entry Name Protein Name Type Information
42737 Q02936 HH_DROME Protein hedgehog (EC 3.1.-.-) [Cleaved into: Protein hedgehog N-product (Hh-Np) (N-Hh)] DISRUPTION PHENOTYPE RNAi-mediated knockdown severely reduces adult survival following the ingestion of E.carotovora. Abolishes Cad99C-dependent formation of endosomes and DUOX-dependent up-regulation of reactive oxygen species (ROS) in the intestines of adults fed bacteria-derived uracil. {ECO:0000269|PubMed:25639794}.