Mine Disruption Phenotype

Gene Info

  • Species:Fly (Drosophila melanogaster)
  • GeneID:43505
  • Symbol:Wdr24
  • Description:WD repeat domain 24
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Gene ID Entry Entry Name Protein Name Type Information
43505 Q9XZ25 WDR24_DROME GATOR complex protein WDR24 (WD repeat-containing protein 24) DISRUPTION PHENOTYPE No effect on viability. Decreased TORC1 complex activity. Decreased body size and weight. Mutant females have small ovaries, reduced egg chamber growth and exhibit a 90% reduction in eggs laid per day. Activation of autophagy and accumulation of autolysosomes independent of nutritional status. {ECO:0000269|PubMed:27166823}.