Mine Disruption Phenotype

Gene Info

  • Species:Fly (Drosophila melanogaster)
  • GeneID:44448
  • Symbol:scrib
  • Description:scribble
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Gene ID Entry Entry Name Protein Name Type Information
44448 Q7KRY7 SCRIB_DROME Protein lap4 (Protein scribble) (Protein smell-impaired) DISRUPTION PHENOTYPE Flies exhibit aberrant cell shape and loss of the monolayer organization of embryonic epithelia creating a corrugated cuticular surface that is riddled with holes hence the gene name scribble. Misdistribution of apical proteins and adherens junctions to the basolateral cell surface is also exhibited. {ECO:0000269|PubMed:10688207}.