| 259303 | Q504J1 | CASPB_DANRE | Caspase b (EC 3.4.22.58) (Caspase 19a) [Cleaved into: Caspase b subunit p20; Caspase b subunit p10] | DISRUPTION PHENOTYPE | Impaired pyroptosis in response to bacterial infection with E.piscicida (PubMed:30076291). Morpholino knockdown results in no observed phenotype (PubMed:30076291). Morpholino knockdown results in impaired gut bacterial clearance following bacterial infection with E.piscicida (PubMed:30076291). Morpholino knockdown results in pericardial edema, erosion of the tail fin and body axis, and impaired up-regulation of il1b, tnfa, il6, il8, il10 and ifng1 cytokines in response to bacterial lipopolysaccharides (LPS) (PubMed:30076291). {ECO:0000269|PubMed:30076291}. |