Mine Disruption Phenotype

Gene Info

  • Species:Zebrafish (Danio rerio)
  • GeneID:30225
  • Symbol:smo
  • Description:smoothened, frizzled class receptor
Export (tab separated) Export to Excel
Gene ID Entry Entry Name Protein Name Type Information
30225 Q5RH73 SMO_DANRE Protein smoothened DISRUPTION PHENOTYPE Abnormalities in body size, abnormal development of the central nervous system, adaxial mesoderm, cartilage and pectoral fins, and reduced expression of ptc1 and foxa2/axial with most mutant embryos dying by the end of day 4 although some survive to day 6 (PubMed:11493557). Expansion of venous cells with a reciprocal loss of arterial cells (PubMed:20193674). {ECO:0000269|PubMed:11493557, ECO:0000269|PubMed:20193674}.