Gene ID | Entry | Entry Name | Protein Name | Type | Information | 30225 | Q5RH73 | SMO_DANRE | Protein smoothened | DISRUPTION PHENOTYPE | Abnormalities in body size, abnormal development of the central nervous system, adaxial mesoderm, cartilage and pectoral fins, and reduced expression of ptc1 and foxa2/axial with most mutant embryos dying by the end of day 4 although some survive to day 6 (PubMed:11493557). Expansion of venous cells with a reciprocal loss of arterial cells (PubMed:20193674). {ECO:0000269|PubMed:11493557, ECO:0000269|PubMed:20193674}. |
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