Mine Disruption Phenotype

Gene Info

  • Species:Zebrafish (Danio rerio)
  • GeneID:405801
  • Symbol:rbm24a
  • Description:RNA binding motif protein 24a
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Gene ID Entry Entry Name Protein Name Type Information
405801 Q76LC6 RBM24_DANRE RNA-binding protein 24 (RNA-binding motif protein 24) (RNA-binding protein SEB-4) DISRUPTION PHENOTYPE Morpholino knockdown of the protein leads to death at 6 days post-fertilization (dpf) due to heart growth defects and absence of blood circulation, despite the presence of a beating heart (PubMed:22345307). Show reduced heart contractility from 30 hours post-fertilization (hpf), onwards (PubMed:22345307). Display defects in sarcomere organization from 33 hpf, onwards (PubMed:22345307). Show altered expression of key genes necessary for sarcomere formation (PubMed:22345307). {ECO:0000269|PubMed:22345307}.