Mine Disruption Phenotype

Gene Info

  • Species:Zebrafish (Danio rerio)
  • GeneID:406291
  • Symbol:katnb1
  • Description:katanin p80 (WD repeat containing) subunit B 1
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Gene ID Entry Entry Name Protein Name Type Information
406291 Q7ZUV2 KTNB1_DANRE Katanin p80 WD40 repeat-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin) DISRUPTION PHENOTYPE Results in a significant reduction in midbrain size. A wide spectrum of defects in gastrulation and formation of anterior structures are noticed, ranging from milder microcephaly to more severe anencephaly and early embryonic death. {ECO:0000269|PubMed:25521378, ECO:0000269|PubMed:25521379}.