| 406783 | F1RCY6 | RENT1_DANRE | Regulator of nonsense transcripts 1 (EC 3.6.4.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up-frameshift suppressor 1 homolog) | DISRUPTION PHENOTYPE | Morpholino knockdown leads to both intermediate and severe phenotypes of abnormal embryonic development (PubMed:21227923, PubMed:19414594). Intermediate phenotypes show developmental delay, including aberrant formation of the head, tail, eye placodes and somites (PubMed:21227923, PubMed:19414594). Severe phenotypes show severe developmental arrest, including yolk extension defects, and lack of recognizable morphological development (PubMed:21227923, PubMed:19414594). High mortality rates of 80% to 85% at 5 days post-fertilization (PubMed:19414594). Increase in premature stop codon containing slc24a5 mRNA transcript levels in melanocytes (PubMed:21227923, PubMed:19414594). {ECO:0000269|PubMed:19414594, ECO:0000269|PubMed:21227923}. |