Mine Disruption Phenotype

Gene Info

  • Species:Zebrafish (Danio rerio)
  • GeneID:406825
  • Symbol:fbxw11b
  • Description:F-box and WD repeat domain containing 11b
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Gene ID Entry Entry Name Protein Name Type Information
406825 A0A2R8RWN9 FB11B_DANRE F-box and WD repeat domain-containing 11-B DISRUPTION PHENOTYPE Knockdown of both fbxw11a and fbxw11b results in abnormally developed pectoral fins and heart edema by day 3 post-fertilization (3 dpf). At 5 dpf, knocked-down embryos show periocular edema, small and misshapen eyes, and abnormal development of the jaw. {ECO:0000269|PubMed:31402090}.