Mine Disruption Phenotype

Gene Info

  • Species:Zebrafish (Danio rerio)
  • GeneID:445055
  • Symbol:rab18b
  • Description:RAB18B, member RAS oncogene family
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Gene ID Entry Entry Name Protein Name Type Information
445055 Q6DHC1 RB18B_DANRE Ras-related protein Rab-18-B DISRUPTION PHENOTYPE The most common abnormalities observed at 3 days post-fertilization are microphthalmia, microcephaly, pericardial edema, delayed jaw formation, a reduced overall body size, and a general developmental delay. Further characterization revealed that the rab18b morphants have delayed retinal development and abnormal retinal lamination, residual nucleated lens fiber cells, widely open choroid fissure, and microphthalmia at day 3. {ECO:0000269|PubMed:21473985}.