Mine Disruption Phenotype

Gene Info

  • Species:Zebrafish (Danio rerio)
  • GeneID:558581
  • Symbol:sart3
  • Description:spliceosome associated factor 3, U4/U6 recycling protein
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Gene ID Entry Entry Name Protein Name Type Information
558581 B3DJT0 SART3_DANRE Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3) DISRUPTION PHENOTYPE The egy mutant embryos that lack detectable sart3 expression display microcephaly, microphthalmia and die by 7 to 8 dpf. Pharyngeal arch formation is defective resulting in a thymus devoid of lymphocytes and exocrine pancreas development is also impaired. {ECO:0000269|PubMed:17416673}.