Mine Disruption Phenotype

Gene Info

  • Species:Zebrafish (Danio rerio)
  • GeneID:561411
  • Symbol:yap1
  • Description:Yes1 associated transcriptional regulator
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Gene ID Entry Entry Name Protein Name Type Information
561411 Q1L8J7 YAP1_DANRE Transcriptional coactivator YAP1 (Yes-associated protein 1) (zYAP) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog) DISRUPTION PHENOTYPE Embryos display a small head with smaller eyes than normal and fewer cartilages in the branchial arches. Marked increase in cell death in brain (PubMed:19393221). Incomplete epiboly at gastrulation, characterized by blastopore closure defects and impaired axis formation (PubMed:21687713). {ECO:0000269|PubMed:19393221, ECO:0000269|PubMed:21687713}.