Mine Disruption Phenotype

Gene Info

  • Species:Zebrafish (Danio rerio)
  • GeneID:565431
  • Symbol:golga2
  • Description:golgin A2
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Gene ID Entry Entry Name Protein Name Type Information
565431 A1IH00 GOGA2_DANRE Golgin subfamily A member 2 (Golgin A2) (cis-Golgi matrix protein GM130) DISRUPTION PHENOTYPE Morpholino knocked-down fishes have smaller brain and significantly diminished motility compared to controls, in association with disorganized muscle fibers. Morphants die between 3-4 days post-fertilization (dpf). Other organs such as eyes and heart are not affected by golga2 knockdown. {ECO:0000269|PubMed:26742501}.