Mine Disruption Phenotype

Gene Info

  • Species:Zebrafish (Danio rerio)
  • GeneID:569810
  • Symbol:smg1
  • Description:SMG1 nonsense mediated mRNA decay associated PI3K related kinase
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Gene ID Entry Entry Name Protein Name Type Information
569810 C5J7W8 SMG1_DANRE Serine/threonine-protein kinase SMG1 (smg-1) (EC 2.7.11.1) (Nonsense-mediated mRNA decay-associated PI3K-related kinase SMG1) DISRUPTION PHENOTYPE Morpholino knockdown results in reduced slc24a5 expression in wild-type embryos however expression is still detectable in the body and retinal pigment epithelium (PubMed:19414594). In 50% of the embryos expression of slc24a5 is restricted to the retina (PubMed:19414594). {ECO:0000269|PubMed:19414594}.